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A meta-analysis also reported diagnoses of medullary thyroid carcinoma in patients taking GLP-1RAs, reinforcing the at-risk status as a contraindication to GLP-1RA treatment

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The typical lipid profile pattern that accompanies obesity includes elevated triglycerides, reduced HDL-C, elevated non-HDL-C, elevated apoB, and increased proportion of LDL-C [10, 13]